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If your target was a game animal more than a hundred yards away wounding the animal with what was essentially a non-expanding fmj projectile would be unethical but hitting a feral recidivistic predatory humanoid who was trying to kill you would be an effective defensive measure.Ĭlick to expand.Shooting a game animal at 100 yards where your impact velocity is down to something like 900 feet per second would not be very effective in terms of a humane kill whether the bullet expanded or not. The 45 with expanding bullets would have greater lethality at closer ranges but the 300 would retain more energy and have a better trajectory at longer ranges although lethality at longer ranges would be less than optimum compared to something like a 30-30 with expanding bullets at higher (supersonic) impact velocities.īut the necessary degree of lethality needed would depend on what your target was. The theoretical advantage of to the suppressed and subsonic 45 is that you could go to a heavier bullet than 220 grains, which would be 250 grains, and most 45 ACP ammo is loaded to 230 grains.Īnd the theoretical advantage of the suppressed and subsonic 300 BO would be that a 30 caliber 220 grain bullet has far better sectional density and ballistic coefficient than the same weight 451 projectile which would give you greater penetration.